Sanofi and Luminostics have signed an agreement to evaluate a collaboration on a self-testing solution for COVID-19, using Luminostics’ technology.
Luminostics would contribute its technology for consumer-diagnostics for COVID-19 testing while Sanofi would bring its clinical research testing experience and capabilities. The goal is to provide a smartphone-based solution that eliminates the current need for healthcare professional administration or laboratory tests.
Alan Main, executive vice president, head of Sanofi Consumer Healthcare, said: “This partnering project could lead to another important milestone in Sanofi’s fight against COVID-19. The development of a self-testing solution with Luminostics could help provide clarity to an individual – in minutes – on whether or not they are infected. Following this week’s announcement of an unprecedented partnership with GSK in the hunt for a vaccine, our company’s ambition is to continue to find other ways to help solve this pandemic situation.”
The goal of this collaboration is to provide a consumer-based test that can detect the COVID-19 virus with high sensitivity and specificity from respiratory samples. The total time from specimen collection to results is expected in the range of 30 minutes or less. It is based on Luminostics’ technology that uses a consumer smartphone’s optics, controlled by an iOS/Android app paired with an inexpensive adapter, in combination with “glow-in-the-dark” nanochemistry and signal processing artificial intelligence.
The diagnostic platform is composed of:
- an iOS/Android app to instruct a user on how to run the test, capture and process data to display test results, and then to connect users with a telehealth service based on the results;
- a reusable adapter compatible with most types of smartphones; and
- consumables for specimen collection, preparation, and processing.
During the current COVID-19 crisis it became obvious that rapid, reliable mass testing is one of the key strategies for successful containment of a pandemic outbreak. While point-of-care tests were made available relatively quickly – although not in a sufficient quantity – no over-the-counter (OTC) self-testing solution is currently available. A rapid self-testing solution would come with advantages, including:
- access and availability to patients at thousands of points-of-sale including e-commerce;
- no further interpersonal contact necessary to conduct the testing, thereby lowering the infection risk for patient, HCP, and laboratory staff; and
- immediate availability of results allowing fast decision making, providing consumers both public health and out-of-pocket cost benefits.
Sanofi is already engaged in multiple clinical trials evaluating current treatment options (Kevzara and Plaquenil) in patients suffering from COVID-19 as well as two vaccine programs.
Based on Luminostics’ existing technology and protypes, both companies envisage to start development activities in the coming weeks. In parallel, both parties expect to execute a final collaboration agreement including a plan for accelerated ramp up of necessary manufacturing capabilities. If development activities can be successfully conducted, the aim is to have an OTC self-testing solution ready before the end of 2020, subject to obtaining required regulatory clearances.